Colts quarterback Andrew Luck is 7-of-8 for 66 yards, three touchdowns and no interceptions in the 23-21 win over the Oakland Raiders on Sunday.
The Colts had been leading 21-13 at halftime.
The Raiders scored three touchdowns on a 44-yard field goal by Jack Del Rio with 4:15 remaining in the first quarter and scored two touchdowns on their next possession on a 46-yard pass from Del Rio to tight end Hunter Henry.
Del Rio completed 7-for-8 passes for 106 yards and a touchdown, including a 26-yarder that was the longest of his career.
He had no interceptions and was sacked once.
It was the first loss for the Raiders this season.
Luck threw for 317 yards and two touchdowns.
Raiders center Travis Frederick missed the game with a knee injury and is doubtful for the game.
The NFL is also considering a suspension for Del Rio, who has two interceptions and has been held in contempt of court in the past.
The two teams played in Oakland on Jan. 15.
Raiders linebacker Kiko Alonso also missed the contest with a hamstring injury.
Delruys suspension comes just one day after his agent was arrested in New York on charges related to an alleged prostitution ring, including an allegation that he took $60,000 in cash from an undercover detective.
Luck is 6-of of 11 for 66 points.
He also threw for a career-high 358 yards and six touchdowns.
The loss moves Oakland to 2-8 in its last 10 games against the Colts, including 0-4 since their season-opening win in Baltimore on Sept. 12.
The win was the Raiders’ eighth straight and second straight in the series.
Oakland lost its last two games, the most recent coming on Sept and Oct. 18, when Luck threw five touchdowns and three interceptions.
Indianapolis is 3-3 in games Luck has started.
The last time Luck was held without a touchdown or a touchdown pass was Sept. 22, when the Colts lost 30-16 at Buffalo.
Indianapolis quarterback Andrew Schefter reported on SiriusXM NFL Radio on Monday that Schefter believes Luck is “getting a little better” and that he feels “a little better.”
Indianapolis was down 28-7 in the fourth quarter and the Raiders won it 31-27 on a TD pass from Robert Woods.
Schefter said Luck has “always been a guy that gets better each day.”
The Colts won the turnover battle and held Raiders quarterback Philip Rivers to just one first down.
Rivers threw for 193 yards and three touchdowns, and Del Rio threw for three touchdowns.
It marked the third time this season that the Colts have won the game when Del Rio is the starting quarterback.
The team has won two straight in Oakland.
The teams have met just once, a 27-27 overtime loss in Indianapolis in 2017.